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Losing Weight

Obesity May Cause Brain Damage

Obesity May Cause Brain Damage

  • February 3, 2011 1:32 pm
  • 11 comments

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Centers for reward and appetite regulation in the brains of overweight people have less volume and display structural damage, reports a new study. To make matters worse, increased inflammatory markers due to obesity indicate that this damage could be an ongoing process.

Water and Inflammation

Researchers from the Nathan Kline Institute for Psychiatric Research in New York examined the brains of 44 obese and 19 men of normal weight with the the help of magnetic resonance imaging (MRI), analysing both the volume and water content of different brain regions, as higher than normal amounts of of water indicates damaged nerve tissue.

Simultaneously they also measured the amount of the protein fibrinogen in the blood stream, as this type of protein goes together with inflammations in the nervous system.

The results of their study showed that a higher fibrinogen level was linked to obesity, which already previous studies had discovered, but also that this inflammation was inflicting damage specifically on the orbitofrontal cortex and the amygdala.

Addictive Damage

These regions are involved in the body’s regulation of satiety and tasting ability and are well-known in addiction research for their role of influencing a person’s decision-making processes.

It’s the dosage that makes the obese.

Similarly to what drug and alcohol abusers experience, who need to increase their dosages to get the effect they experienced in the beginning, an overweight person as well might need to increase his food intake to feel satiated and satisfied with what he has eaten. This of course would lead to a higher body weight, in turn leading to more brain damage, making more stimulation through food necessary.

If this possible link proves to be true, this would be a very vicious circle.

Picture courtesy of “Kanaka Menehune“.

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Latest Comments

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11 Comments

  1. Rubby90 says:
    February 3, 2011 at 8:37 pm

    A good and informative read!

    Reply
    • evilcyber says:
      February 4, 2011 at 7:04 pm

      Thanks Rubby!

      Reply
  2. Myschly says:
    February 4, 2011 at 4:25 pm

    Seems the similarity in danger from obesity and hard drugs keeps on growing. Wonder how long it’ll take before this is recognized on a political level.

    The same govts that have no problem dictating what drugs can & can’t be used, seem reluctant to even raise taxes on food we know to be addictive.

    Alas, the policies that work aren’t the ones that will be put in place, just as with the war on drugs, money will be spent on worthless crap, & nothing gets fixed.

    Reply
    • evilcyber says:
      February 4, 2011 at 7:03 pm

      Well, the food industry does have a strong lobby.

      Reply
  3. Growel says:
    February 4, 2011 at 4:26 pm

    The first sentence implies that overweight people have less structural damage in their brains. Perhaps it could be reworded to something like “[…] the brains of overweight people have less volume as well as structural damage […]”

    Just a suggestion.

    Reply
    • evilcyber says:
      February 4, 2011 at 7:04 pm

      Point well taken and corrected!

      Reply
      • Growel says:
        February 4, 2011 at 7:34 pm

        Glad I could help 🙂
        (Your correction was better than my suggestion too.)

        Reply
  4. Dave says:
    February 4, 2011 at 10:59 pm

    Seems a logical step to assume that the brain damage was what caused to eating problem in the first place, no?

    Reply
    • evilcyber says:
      February 5, 2011 at 9:39 pm

      Yes, it would be interesting to know if these people had problems in those areas right after birth.

      Reply
  5. jtanderson121 says:
    February 6, 2011 at 12:04 am

    Lol I wonder if that chick chowing down on the turkey leg would be livid if she ever sees that her picture was used in an article about obesity!

    Reply
  6. Kael says:
    February 6, 2011 at 10:14 pm

    Another thing to consider is all the strange things in processed foods that some classify as neurotoxins. A healthy diet is not only good for the body, it’s good for the head too.

    Reply

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